Faculty of Performance, Visual Arts & Communications

School of Design

Giuseppe Tronci

Senior Research Fellow in Textile Materials Innovation for Healthcare

0113 343 8779

Wellcome Trust Brenner Building, Room 7.17 (St. James’s University Hospital)

Laurea Magistrale (Turin Polytechnic -IT), PhD (University of Potsdam -DE)

Senior Research Fellow at Clothworkers’ Centre for Textile Materials Innovation for Healthcare (2013-, University of Leeds), Research Fellow at WELMEC Centre of Excellence in Medical Engineering (2011-2013, University of Leeds), PhD fellow at Helmholtz-Zentrum Geesthacht Biomaterials Centre and University of Potsdam (2006-2010, Germany)

Biography

Dr Tronci is a Senior Research Fellow within the Clothworkers’ Centre for Textile Materials Innovation for Healthcare (CCTMIH) with an affiliation at Leeds School of Dentistry. His research profile lies at the interface of biomaterials science, macromolecular science, and textile technology. He is particularly interested in the biomimetic design of functional material systems for relevant clinical applications, e.g. in the context of musculoskeletal and chronic wound care. He joined CCTMIH in 2013 following his post-doctoral training within the WELMEC centre of excellence in medical engineering (University of Leeds, UK). Prior to joining the University of Leeds, he completed his undergraduate studies in biomedical engineering (Turin Polytechnic, Italy), followed by a PhD in biomaterials (University of Potsdam, Germany), where he studied the structure-property-function relationships of defined biopolymer-based materials.

Research Interests

  • Biomimetic design of functional material systems, e.g. hydrogels
  • Degradable polymers for the controlled loading/release of drugs
  • Formation of functional nonwovens based on defined macromolecular assemblies
  • Structure-property-function relationships in textile-based biomaterials
  • Biomaterial-cell interactions
  • Biomaterial translation in to the clinic

Teaching

TEXT 5135 Medical Textiles: Biomaterials and tissue engineering

TEXT 5116: Research Dissertation

Publications

Journal articles

  • Tronci G, Kanuparti RS, Arafat MT, Yin J, Wood DJ, Russell SJ (2015) “Wet-spinnability and crosslinked fibre properties of two collagen polypeptides with varied molecular weight”, International Journal of Biological Macromolecules. 81: 112-120.
    DOI: 10.1016/j.ijbiomac.2015.07.053, Repository URL: http://eprints.whiterose.ac.uk/88536/

  • Arafat MT, Tronci G, Yin J, Wood DJ, Russell SJ (2015) “Biomimetic wet-stable fibres via wet spinning and diacid-based crosslinking of collagen triple helices”, Polymer (United Kingdom). 77: 102-112.
    DOI: 10.1016/j.polymer.2015.09.037, Repository URL: http://eprints.whiterose.ac.uk/90093/

  • Bulman SEL, Goswami P, Tronci G, Russell SJ, Carr C (2015) “Investigation into the potential use of poly(vinyl alcohol)/methylglyoxal fibres as antibacterial wound dressing components”, Journal of Biomaterials Applications. 29.8: 1193-1200.
    DOI: 10.1177/0885328214556159, Repository URL: http://eprints.whiterose.ac.uk/83833/

  • Neffe AT, Pierce BF, Tronci G, Ma N, Pittermann E, Gebauer T, Frank O, Schossig M, Xu X, Willie BM, Forner M, Ellinghaus A, Lienau J, Duda GN, Lendlein A (2015) “One step creation of multifunctional 3D architectured hydrogels inducing bone regeneration”, Advanced Materials. 27.10: 1738-1744.
    DOI: 10.1002/adma.201404787, Repository URL: http://eprints.whiterose.ac.uk/85025/

  • Neffe AT, Pierce BF, Tronci G, Ma N, Pittermann E, Gebauer T, Frank O, Schossig M, Xu X, Willie BM, Forner M, Ellinghaus A, Lienau J, Duda GN, Lendlein A (2015) “Hydrogels: one step creation of multifunctional 3D architectured hydrogels inducing bone regeneration.”, Advanced Materials. 27.10: 1800-1800.
    DOI: 10.1002/adma.201570071, Repository URL: http://eprints.whiterose.ac.uk/85031/

  • Tronci G, Grant CA, Thomson NH, Russell SJ, Wood DJ (2015) “Multi-scale Mechanical Characterization of Highly Swollen Photo-activated Collagen Hydrogels”, Journal of the Royal Society Interface. 12.102
    DOI: 10.1098/rsif.2014.1079, Repository URL: http://eprints.whiterose.ac.uk/85027/

  • Qiao X, Russell SJ, Yang X, Tronci G, Wood DJ (2015) “Compositional and in Vitro Evaluation of Nonwoven Type I Collagen/Poly-dl-lactic Acid Scaffolds for Bone Regeneration.”, Journal of functional biomaterials. 6.3: 667-686.
    Repository URL: http://eprints.whiterose.ac.uk/88866/

  • Tronci G, Ajiro H, Russell SJ, Wood DJ, Akashi M (2014) “Tuneable drug-loading capability of chitosan hydrogels with varied network architectures”, Acta Biomaterialia. 10.2: 821-830.
    DOI: 10.1016/j.actbio.2013.10.014, Repository URL: http://eprints.whiterose.ac.uk/80783/

  • Tronci G, Russell SJ, Wood DJ (2013) “Photo-active collagen systems with controlled triple helix architecture”, Journal of Materials Chemistry. B. 30.1: 3705-3715.
    DOI: 10.1039/c3tb20720j, Repository URL: http://eprints.whiterose.ac.uk/80784/

  • Tronci G, Doyle A, Russell SJ, Wood DJ (2013) “Triple-helical collagen hydrogels via covalent aromatic functionalization with 1,3 phenylenediacetic acid”, Journal of Materials Chemistry B. 40.1: 5478-5488.
    DOI: 10.1039/C3TB20218F, Repository URL: http://eprints.whiterose.ac.uk/80785/

  • Pierce BF, Tronci G, Rössle M, Neffe AT, Jung F, Lendlein A (2012) “Photocrosslinked co-networks from glycidylmethacrylated gelatin and poly(ethylene glycol) methacrylates.”, Macromol Biosci. 12.4: 484-493.
    DOI: 10.1002/mabi.201100232

  • Neffe AT, Tronci G, Alteheld A, Lendlein A (2010) “Controlled Change of Mechanical Properties during Hydrolytic Degradation of Polyester Urethane Networks”, MACROMOL CHEM PHYS. 211.2: 182-194.
    DOI: 10.1002/macp.200900441

  • Tronci G, Neffe AT, Pierce BF, Lendlein A (2010) “An entropy-elastic gelatin-based hydrogel system”, J MATER CHEM. 20.40: 8875-8884.
    DOI: 10.1039/c0jm00883d

  • Gharaei R, Tronci G, Davies RP, Goswami P, Russell SJ “An investigation into the nano-/micro-architecture of electrospun poly(ε-caprolactone) and self-assembling peptide fibres”, MRS Advances. (Accepted)
    Repository URL: http://eprints.whiterose.ac.uk/93540/

  • Tronci G, Grant CA, Thomson NH, Russell SJ, Wood DJ “Influence of 4-vinylbenzylation on the rheological and swelling properties of photo activated collagen hydrogels”, MRS Advances. (Accepted)
    Repository URL: http://eprints.whiterose.ac.uk/92566/

Chapters

  • Durham ER, Tronci G, Yang X, Wood DJ, Russell SJ (2015) “Nonwoven scaffolds for bone regeneration”, In: Biomedical Textiles for Orthopaedic and Surgical Applications: Fundamentals, Applications and Tissue Engineering. 45-65
    DOI: 10.1016/B978-1-78242-017-0.00003-9

Conference papers

  • Tronci G, Doyle A, Russell SJ, Wood DJ (2013) Structure-property-function relationships in triple helical collagen hydrogels. 2012 MRS Fall Meeting & Exhibit- Biomimetic, Bio-inspired and Self-Assembled Materials for Engineered Surfaces and Applications Proceedings: MRS Online Proceedings Library Cambridge University Press. 1498: 145-150.
    DOI: 10.1557/opl.2012.1653, Repository URL: http://eprints.whiterose.ac.uk/85104/

  • Tronci G, Durham E, Russell SJ, Wood DJ (2011) Bioinspired porous materials for mineralized tissue formation. 4th International Conference on the Mechanics of Biomaterials and Tissues (2011)

Conference presentations

  • Tronci G, Ajiro H, Russell SJ, Wood DJ, Akashi M (2013) Bioactive chitosan hydrogels with varied network architecture and tuneable drug loading capability. TERMIS-AP (2013)

  • Tronci G (2013) Design of biomimetic systems with defined network architecture and tuneable material properties and functionalities. Powder Technology Workshop – 25 years of Powder Technology at EPFL (2013)

Patents

  • Tronci G, Russell SJ, Wood DJ (2014) Improvements in and relating to collagen based materials.

Thesis / Dissertations

  • Tronci G Synthesis, characterization, and biological evaluation of gelatin-based scaffolds.

Research Projects & Grants

  • Wellcome Trust-ISSF academic fellowship at University of Michigan (USA, 2015)
  • “Tendon-bone tissue connector for rotator cuff tear repairs”, EPSRC MeDe Fresh Ideas Fund (2015, PI), joint with Newcastle University and UCL
  • “Investigation of the short and long range organisation in photo-activated collagen hydrogels” (MA-2796), European Synchrotron Radiation Facility (2015, PI)
  • “Water Stable Collagen Wound Dressing Materials”, IKC PoC, University of Leeds (2014, Co-I)
  • “Stratified design and manufacture of nonwoven collagen scaffolds”, MeDe Innovation Centre, University of Leeds (2014-2016, Co-I)
  • “Design of responsive chitosan-based hydrogels incorporating bioactive molecules as potential stem cell niches”, Great Britain Sasakawa Foundation Butterfield award (2012, Co-I)

Responsible for:

  • Development of muti-disciplinary research networks in the area of textile materials and healthcare (collaborations with the School of Dentistry, School of Healthcare, IMBE and St James’ Hospital)
  • Supervision and development of CCTMIH-funded research projects
  • Supervision of MeDe and IKC funded research projects
  • Supervision of CDT TERM (iMBE) research projects

Research Centres & Groups

Textile Materials Technology

PhD Thesis

G. Tronci, “Synthesis, characterization and biological evaluation of gelatin-based scaffolds”, University of Potsdam (Germany, 2010), arXiv:1101.1651

Professional Practice

  • Referee in peer-reviewed journals such as “Chemical Communications”, “Journal of Materials Chemistry”, “Soft Matter”, “Chemical Society Reviews” and “RSC Advances”
  • PGCert in Professional Innovation Management, University of Leeds (2014)

Links

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